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For us, safety is more than just a list of ingredients that are paraben-free, silicone-free, and fragrance-free. We evaluate each ingredient based on its ability to mimic your skin’s natural functions, its ability to work synergistically within the formula, and its proven safety profile.
Our formulas are COSMOS NATURAL / COSMOS ORGANIC certified and audited by Ecocert Greenlife, and we are committed to minimizing the presence of allergens. Our approach is to work in harmony with your skin, its structure, and its balance, and to support you over the long term.
Is this "Pro-Retinol" booster serum right for you?
Choose Pro-Retinol if you want to renew your skin, restore elasticity, and smooth out wrinkles, but your skin doesn’t tolerate retinoids well. Its Bakuchiol activates cellular mechanisms related to skin renewal and collagen synthesis without being retinol, converting to retinoic acid, or requiring a retinization process.
To support this renewal, it combines hyaluronic acid and CICA with an antioxidant complex of red grape, goji berries, and ginkgo biloba. Together, they maintain hydration, soothe the skin, and help protect collagen from oxidative stress. A highly tolerable alternative that can be used year-round, day or night, and during pregnancy.
How Pro-Retinol Works
Your skin after 1 day, 7 days, and with continued use
Hydration and plumping effect: Hyaluronic acid attracts and retains moisture, adding volume and elasticity while reducing lines and wrinkles.
Soothes without a retinization process: Bakuchiol is not a retinoid and does not require an adjustment period. CICA complements its action by helping to reduce tightness, redness, and discomfort.
First line of antioxidant defense: Ginkgo, red vine, goji berries, and bakuchiol begin to neutralize free radicals and protect the skin from daily oxidative stress.
Smoother, more supple texture: continuous hydration and gradual renewal improve the skin’s softness and make fine lines and roughness less visible.
More radiance and vitality: Ginkgo and Red Vine promote a fresher, less puffy appearance, while Goji Berries boost the face’s antioxidant protection.
Progressive and gentle renewal: 2% Bakuchiol promotes orderly renewal without causing the intense flaking or adaptation period associated with retinoids.
Improved firmness and smoother wrinkles: Bakuchiol acts on mechanisms related to collagen synthesis, progressively improving firmness and the appearance of fine lines and wrinkles.
More even and radiant skin tone: The network of antioxidants helps limit oxidative damage that dulls the complexion and accentuates uneven skin tone.
Skin elasticity and resilience: The combination of Bakuchiol, CICA, hyaluronic acid, and botanical antioxidants protects the skin’s support structures and helps maintain more elastic, smooth, and resilient skin.
plant-based, biomimetic, derived from natural sources
Ingredients Packed with Science

Hyaluronic acid attracts and locks in moisture in your skin—oil-free, lightweight, and non-clogging—to keep it naturally hydrated.
Hydration is the foundation of skin longevity. That’s why natural hyaluronic acid isn’t just a trendy ingredient—it’s the building block upon which you’ll lay the foundation for your skin’s health. At DHYVANA, we select dual-action molecular weights (10–50 kDa) certified by EcoCert, derived from the natural fermentation of glucose. These work through biomimicry: they repair the outer layers by restoring the natural protective barrier that prevents water loss. Of course, our hyaluronic acid is 100% vegan and GMO-free.
Just as with your skin’s structural proteins—collagen and elastin—the skin’s natural moisture reserves decrease over the years. That’s why incorporating a hyaluronic acid serum helps restore this lost moisture and improve your skin’s longevity.
All of our organic skincare products work through biomimicry, and more specifically, our low- and medium-molecular-weight hydrating hyaluronic acid penetrates the skin through this mechanism. The result: they reach the different layers of the skin and deliver the various benefits you expect from a serum— fewer wrinkles, fewer signs of aging, more hydrated skin, and much smoother skin.
The serum serves a specific purpose: to reach the deepest layers of the skin. In your moisturizer, hyaluronic acid acts as an external shield that works in synergy with your skin’s barrier function. This mechanism is fascinating: without adding extra lipids but by working in synergy with them, it prevents transepidermal water loss. As a result, it balances combination and oily skin, nourishes dry skin, and keeps normal skin perfectly balanced—all without clogging the pores.
Absolutely. And here’s why: the eye area (dark circles) requires ingredients that meet several criteria. They need to be highly moisturizing, hypoallergenic, and not overly greasy. The skin in this area is very thin and particularly mobile (just think about how much you move your eyes throughout the day), which is why it’s essential to provide extra hydration.
In this regard, we’d like to remind you of DHYVANA’s Radical Safety principle. If you’re not familiar with this concept, be sure to check out our“Formulation Principles” section; at DHYVANA, we always formulate products for sensitive skin, using no harmful ingredients and eliminating anything that doesn’t benefit your skin. And you’re going to love this: our serums are designed to be applied around the eye area, and so are our creams. In each product’s description, we explain exactly how to use them.
It is primarily a hydrating ingredient, and in fact acts like a sponge. Its function is to absorb water, and when combined with other ingredients, it also provides moisturizing benefits: in other words, it helps seal in that water and retain moisture.
The effect of this hydration on your skin depends on its molecular weight. Low-molecular-weight hyaluronic acid penetrates down to the deepest layers. Its effect is less visible to the eye, but in return, it provides deep, long-lasting hydration. This is key to building the foundation of your Skin Longevity. Then there’s medium- and high-molecular-weight hyaluronic acid, which acts on the outermost layers of the skin and strengthens your protective barrier. You’ll notice its plumping effect in the mirror (fewer wrinkles), and it serves as the first line of defense against dehydration.
Which is better? At DHYVANA , we use both complementary approaches, both of which are necessary: low molecular weight (approximately 10 kDa) and medium-to-high molecular weight (up to 50 kDa). This way, you’ll notice visible hydration while simultaneously building a strong, invisible foundation.
Hyaluronic acid really is an ingredient that works wonderfully in all kinds of skincare routines. Since it’s non-greasy, it’s suitable for daytime routines, which are typically lighter, require a more fluid hydration, and allow you to apply makeup or protect your skin from pollution. And most importantly: you shouldn’t skip hyaluronic acid in your nighttime routine. At night, in sync with your skin’s natural repair cycle, it works every day to help your skin build a strong foundation. That’s your daily dose of Skin Longevity.

Natural alternative to synthetic Retinol to fight skin aging
It is extracted from the seeds of the Babchi plant (Psoralea corylifolia). Known colloquially as BioRetinol, it shares a similar molecular structure and exhibits comparable effects on the skin as synthetic Retinol. These effects include promoting collagen production, reducing the appearance of fine lines and wrinkles, and improving skin elasticity. It is not irritating or photosensitive, so it can be used by all skin types, including sensitive, pregnant and lactating.

Centennial botanical used in multiple therapies
It is widely used for its regenerative, healing, antioxidant and anti-inflammatory properties, and generally provides comprehensive anti-aging for all skin types.

Great capacity to improve blood circulation
It also improves the production of collagen and elastin, which helps to keep the skin firm and elastic and prevents premature aging, thanks to its toning, decongestant and anti-inflammatory effect.

With energizing, purifying and stimulating properties
Improves the metabolic functions of cells. It provides a protective, rejuvenating and holistic barrier for both hair and skin tissue.

Venotonic, antioxidant and anti-aging agent
Helps combat venous insufficiency and skin capillary fragility and improves blood circulation in the skin, which translates into a better appearance of the skin as it helps reduce swelling and inflammation.
Get Your Skincare Routine Back on Track
Directions for Use
Remember: Your skin must be clean before you begin so that the hyaluronic acid and active ingredients can penetrate properly.
1. Open the ampoule:Use the break line along the white line.
2. Choose the amount: Use one full ampoule per day if you’re doing the 7-day (or up to 14-day) intensive treatment, or use a smaller amount—like a daily serum—if you prefer to use it for maintenance.
3. Let it work: Wait a few minutes until your skin has fully absorbed it, and then continue with your skincare routine.
4. Finish with your moisturizer: Choose a barrier cream for deeper hydration or a moisturizer with SPF for daytime hydration.
You can use your ampoules day and night, and even combine different treatments to create your own personalized Skin Longevity routine.



Frequently Asked Questions
We’ve created three barrier creams that help you lock in the benefits of your ampoules: Balance is light and fluid, ideal for younger skin or if you’re looking for water-based hydration; Universal offers a blend of lipids and water that’s perfect for normal skin and all skin types; and Supreme nourishes and hydrates even the most dehydrated skin, perfect for mature skin seeking to seal in their treatment with oil-rich hydration.



Bakuchiol is an active ingredient that is 100% plant-based. It is known as BioRetinol because it is the natural alternative to retinol, or “vegan retinol. “
From a molecular perspective, we see that it is composed of a molecule similar to retinol. This molecule stimulates the genes that address deep wrinkles and prevent their formation. This promotes collagen synthesis and elastin renewal. Visible signs of aging, such as wrinkles, are reduced (by about 20% in the first few weeks). It also reduces the loss of elasticity and firmness. In natural and vegan cosmetics, we really like this active ingredient because it doesn’t have the side effects of synthetic retinol. And it delivers visible results, even on sensitive skin.
Both Bakuchiol and Retinol are effective for anti-aging, improving skin elasticity and reducing wrinkles.
If you have delicate skin or prefer more respectful formulas, Bakuchiol is better for those who are looking for a natural option, have sensitive skin, or if you want to avoid the side effects of retinol such as dryness and redness. In other words, it offers comparable results with far superior skin tolerance.
One of the great advantages of Bakuchiol is its high compatibility. Unlike retinol, which can interact with other actives, Bakuchiol can safely be used in the same routine with ingredients such as Vitamin C, hyaluronic acid and other exfoliants such as AHA or BHA.
If you want to build the perfect skin care routine for your skin, we help you with our free skin test – in just 2 minutes!
One of the most frequently asked questions is about the use of Bakuchiol in pregnancy. Experts in the dermatological and cosmetic community agree that
If you have any doubts, from DHYVANA we always recommend that you consult your doctor or dermatologist.
Start with an intensive 7-day treatment using 7 ampoules. This way, you’ll see visible results in no time.
After this first week, the best way to maintain, enhance, and prolong your results is to continue your treatment by using the contents of <1 ml from your ampoules every day.
You can use them for as long as you like, but we recommend using them for at least 4 weeks.
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1 review for Pro-Retinol
Ana (verified owner) –
Estoy encantada con las ampollas como un extra en la rutina diaria. En concreto las de pro-retinol (después de la limpieza nocturna) las siento como un aporte nutritivo extra, antes de aplicarme el aceite Anti-aging Efecto Total.
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